Antinociceptive effect of methanolic extract and alkaloid fractions of Berberis integerrima root in animal models

摘要

Objective: Berberis vulgaris has antioxidant, hepato--renal protective, antibacterial, lipid lowering, anti-inflammatory and antinociceptive activities. The genus Berberis, has another member called Berberis integerrima which has not been studied for antinociceptive activity and therefore, this study was aimed to examine the antinociceptive effect of total extract and alkaloid fractions of Berberis integerrima root in mice.