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Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking active alcoholics

机译：代谢型谷氨酸受体3基因型对非吸烟活动性酒精中毒患者N-乙酰天门冬氨酸水平和神经认知的影响

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摘要

BackgroundWe studied the effects of single nucleotide polymorphisms (SNPs) in the metabotropic glutamate receptor 3 (GRM3) gene on brain N-acetylaspartate (NAA) concentrations and executive function (EF) skills in non-smoking, active alcoholics, and evaluated associations between these variables.

机译：背景我们研究了代谢型谷氨酸受体3（GRM3）基因中的单核苷酸多态性（SNPs）对非吸烟，积极酗酒者的脑N-乙酰天冬氨酸（NAA）浓度和执行功能（EF）技能的影响，并评估了它们之间的关联变量。

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期刊名称 Behavioral and Brain Functions : BBF
作者
Yan Xia; Dongying Ma; Jian Hu; Chunling Tang; Zheng Wu; Lei Liu; Feng Xin;
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作者单位

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年(卷),期 2012(8),-1
年度 2012
页码 42
总页数 11
原文格式 PDF
正文语种
中图分类神经科学;医学行为学;
关键词
Alcohol dependence Metabotropic glutamate receptor 3 Single nucleotide polymorphism N-acetylaspartate Executive function;

机译：酒精依赖;代谢型谷氨酸受体3;单核苷酸多态性;N-乙酰天门冬氨酸;执行功能;

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专利

1. Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics [J] . Yan Xia, Dongying Ma, Jian Hu, Behavioral and Brain Functions . 2012,第1期

机译：代谢型谷氨酸受体3基因型对非吸烟活动性酒精中毒患者N-乙酰天门冬氨酸水平和神经认知的影响
2. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]. [J] . Satow A, Maehara S, Ise S, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第2期

机译：代谢型谷氨酸受体1拮抗剂与代谢型谷氨酸受体5拮抗剂和代谢型谷氨酸受体2/3激动剂在啮齿类动物中的药理作用：选择性变构代谢型谷氨酸受体1拮抗剂FTIDC的详细研究[4- [1-（ [2-氟吡啶-3-基）-5-甲基-1H-1,2,3-三唑-4-基] -N-异丙基-N-甲基-3,6-二氢吡啶-1（2H）-羧酰胺]。
3. Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramine-induced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands. [J] . Nicoletti F Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2005,第5期

机译：代谢型谷氨酸受体和抗抑郁药的神经适应性：丙咪嗪诱导的用代谢型谷氨酸2/3受体配体治疗的小鼠的β-肾上腺素受体下调。
4. Manifold learning visualization of Metabotropic Glutamate Receptors [C] . Martha-Ivon Cardenas, Alfredo Vellido, Jesus Giraldo International Conference of the Catalan Association for Artificial Intelligence . 2014

机译：代谢谷氨酸受体的歧管学习可视化
5. Metabotropic Glutamate Receptors Effects on Feeding [D] . Cano, Jonathan Rene Charles 2015

机译：代谢型谷氨酸受体对饲料的影响
6. Metabotropic Glutamate Receptor 3 Genotype May Predict N-Acetylaspartate Measures in the Dorsolateral Prefrontal Cortex [O] . Stefano Marenco, Sonya U. Steele, Michael F. Egan, -1

机译：代谢型谷氨酸受体3基因型可能预测N-乙酰乙酰天冬氨酸在前外侧额叶皮层的措施。
7. Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics [O] . Xia Yan, Ma Dongying, Hu Jian, 2012

机译：代谢型谷氨酸受体3基因型对非吸烟，活动性酒精中毒患者N-乙酰天门冬氨酸水平和神经认知的影响

Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking active alcoholics

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