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The effect of white kidney bean fertilized with nano-zinc on nutritional and biochemical aspects in rats

机译:白芸豆纳米锌对大鼠营养和生化指标的影响

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摘要

This study aims to estimate the safety of white kidney bean (WKB) fertilized by zinc oxide nanoparticles (ZnO-NPs) via studying changes of liver and kidney function, lipid profile and histological examination for the liver and kidney tissue in rats fed on it. Twenty Four male albino rats were used in this study divided into four groups; the first fed balanced diet (control group), the second fed WKB treated with normal ZnO (nWKB), the third fed WKB treated with 20 ppm ZnO-NPs (tWKB-1), and the fourth fed WKB treated with 40 ppm ZnO-NPs (tWKB-2). The results revealed that WKB treated with ZnO-NPs reduced body weight, food efficiency ratio, relative liver weight, and relative spleen weight were increased as well as the most biochemical parameters exhibited non-significant changes as compared to control group. Meanwhile, tWKB-2 group demonstrated a decrease in alkaline phosphatase and aspartate transaminase activities as compared to nWKB group.
机译:本研究旨在通过研究以肾脏为食的大鼠的肝和肾功能的变化,脂质分布以及肝和肾组织的组织学检查,来评估由氧化锌纳米颗粒(ZnO-NPs)施肥的白芸豆(WKB)的安全性。本研究使用了二十四只雄性白化病大鼠,分为四组。第一个饮食均衡饮食(对照组),第二个饮食WKB用正常ZnO处理(nWKB),第三个饮食WKB用20μppmZnO-NPs处理(tWKB-1),第四个饮食WKB用40μppmZnO-处理NP(tWKB-2)。结果显示,与对照组相比,用ZnO-NPs处理的WKB减轻了体重,食物效率比,相对肝脏重量和相对脾脏重量增加,并且大多数生化参数显示无明显变化。同时,与nWKB组相比,tWKB-2组表现出碱性磷酸酶和天冬氨酸转氨酶活性降低。

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