Performance characteristics between TDx®FLx and TBA™-25FR for the therapeutic drug monitoring of methotrexate

机译：TDx®FLx和TBA™-25FR之间的性能特征用于监测甲氨蝶呤的治疗药物

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BackgroundHigh-dose methotrexate (HDMTX) is used in the treatment of certain malignancies, including leptomeningeal metastases, systemic non-Hodgkin lymphoma, acute lymphoblastic leukemia, and osteosarcoma. High circulating levels of methotrexate can cause severe myelosuppression. The present study aimed to examine the differences in plasma MTX concentrations measured by two immunoassay systems currently available in the Japanese market, a TDX/FLX analyzer and a TBA-25FR analyzer.

机译：背景大剂量甲氨蝶呤（HDMTX）用于治疗某些恶性肿瘤，包括软脑膜转移瘤，全身性非霍奇金淋巴瘤，急性淋巴细胞性白血病和骨肉瘤。甲氨蝶呤的高循环水平可导致严重的骨髓抑制。本研究旨在检查由日本市场上目前可用的两种免疫测定系统，TDX / FLX分析仪和TBA-25FR分析仪测量的血浆MTX浓度的差异。

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期刊名称 Journal of Pharmaceutical Health Care and Sciences
作者
Tetsuya Kaneko; Takashi Fujioka; Yosuke Suzuki; Yuhki Sato; Hiroki Itoh;
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作者单位

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年(卷),期 2016(2),-1
年度 2016
页码 7
总页数 5
原文格式 PDF
正文语种
中图分类药学;
关键词
Methotrexate High-dose Methotrexate Therapeutic drug monitoring Automatic immunoassay systems;

机译：甲氨蝶呤;大剂量甲氨蝶呤;治疗药物监测;自动免疫测定系统;
入库时间 2022-08-17 11:48:27

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专利

1. Performance characteristics between TDx?FLx and TBA?-25FR for the therapeutic drug monitoring of methotrexate [J] . Tetsuya Kaneko, Takashi Fujioka, Yosuke Suzuki, Journal of Pharmaceutical Health Care and Sciences . 2016,第1期

机译：TDx？FLx和TBA？-25FR之间用于甲氨蝶呤治疗药物监测的性能特征
2. Therapeutic Drug Monitoring of Methotrexate in Plasma Using Ultra High-Performance Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry: Necessary After Administration of Glucarpidase in Methotrexate Intoxications [J] . Mulder Midas B., Huisman Ruud, Engels Frederike K., Therapeutic Drug Monitoring . 2018,第4期

机译：使用超高效液相色谱 - 电喷雾电离 - 串联质谱法测定甲氨蝶呤甲氨蝶呤的治疗药物监测：甲氨蝶呤中毒葡萄糖蔗糖酶施用后必需
3. Therapeutic Drug Monitoring of Methotrexate in Plasma Using Ultra High-Performance Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry: Necessary After Administration of Glucarpidase in Methotrexate Intoxications [J] . Mulder Midas B., Huisman Ruud, Engels Frederike K., Therapeutic Drug Monitoring . 2018,第4期

机译：使用超高效液相色谱 - 电喷雾电离 - 串联质谱法测定甲氨蝶呤甲氨蝶呤的治疗药物监测：甲氨蝶呤中毒葡萄糖蔗糖酶施用后必需
4. Validation of Isoniazid for Therapeutic Drug Monitoring in Human Plasma by High-Performance Liquid Chromatography [C] . S.P.V.D. Jaikishin, D.A. Perwitasari, E. Darmawan, Conference on Fundamental and Applied Science for Advanced Technology . 2016

机译：高效液相色谱法验证人血浆治疗药物监测
5. Saliva versus Blood Therapeutic Drug Monitoring of Lithium Among Jordanian Patients [D] . Atiyah, Ahmed Hazim. 2021

机译：约旦患者锂与血液治疗药物监测的唾液
6. Simultaneous Quantification of Methotrexate and Its Metabolite 7-Hydroxy-Methotrexate in Human Plasma for Therapeutic Drug Monitoring [O] . Xinxin Ren, Zhipeng Wang, Yunlei Yun, 1952

机译：同时定量测定人血浆中甲氨蝶呤及其代谢物7-羟基甲氨蝶呤用于治疗药物的监测
7. Performance characteristics between TDx®FLx and TBA™-25FR for the therapeutic drug monitoring of methotrexate [O] . Tetsuya Kaneko, Takashi Fujioka, Yosuke Suzuki, 2016

机译：TDx®FLx和TBA™-25FR之间的性能特征，用于监测甲氨蝶呤的治疗药物

Performance characteristics between TDx®FLx and TBA™-25FR for the therapeutic drug monitoring of methotrexate

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