Reduction in the rate of postoperative delirium by switching from famotidine to omeprazole in Japanese hepatectomized recipients

摘要

BackgroundHepatectomy is a highly invasive procedure with a high probability of postoperative delirium. Treatment with antiulcer drugs is indispensable after hepatectomy for anastomotic ulcer management. The clinical pathway for hepatectomy was reviewed and the antiulcer drug used was switched from famotidine, a H2-receptor antagonist, to omeprazole, a proton pump inhibitor, owing to the pharmacist’s intervention.