Analysis of the association between codon optimality and mRNA stability in Schizosaccharomyces pombe

摘要

BackgroundRecent experiments have shown that codon optimality is a major determinant of mRNA stability in Saccharomyces cerevisiae and that this phenomenon may be conserved in Escherichia coli and some metazoans, although work in Neurospora crassa is not consistent with this model.