Levels of (1→3)-β-D-glucan Candida mannan and Candida DNA in serum samples of pediatric cancer patients colonized with Candida species

摘要

BackgroundSurveillance cultures may be helpful in identifying patients at increased risk of developing invasive candidiasis. However, only scant information exists on the effect of Candida colonization on serum levels of diagnostic biomarkers. This prospective surveillance study determined the extent of Candida colonization among pediatric cancer patients and its possible impact on serum levels of (1-3)-β-D-glucan (BDG), Candida mannan and Candida DNA.