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Efficacy safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: a protocol for a randomIsed controlled Trial (CAP-IT)

机译：阿莫西林治疗社区获得性肺炎的儿童的持续时间和剂量的有效性安全性以及对抗菌素耐药性的影响：一项随机对照试验（CAP-IT）的方案

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IntroductionCommunity-acquired pneumonia (CAP) is a common indication for antibiotic treatment in young children. Data are limited regarding the ideal dose and duration of amoxicillin, leading to practice variation which may impact on treatment failure and antimicrobial resistance (AMR). Community-Acquired Pneumonia: a randomIsed controlled Trial (CAP-IT) aims to determine the optimal amoxicillin treatment strategies for CAP in young children in relation to efficacy and AMR.

机译：简介社区获得性肺炎（CAP）是幼儿抗生素治疗的常见指征。关于阿莫西林的理想剂量和持续时间的数据有限，导致实践差异可能会影响治疗失败和抗菌素耐药性（AMR）。社区获得性肺炎：一项随机对照试验（CAP-IT）旨在确定与功效和AMR相关的小儿CAP阿莫西林治疗的最佳策略。

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期刊名称 BMJ Open
作者
Mark D Lyttle; Julia A Bielicki; Sam Barratt; David Dunn; Adam Finn; Lynda Harper; Pauline Jackson; Colin V E Powell; Damian Roland; Wolfgang Stohr; Kate Sturgeon; Mandy Wan; Paul Little; Saul N Faust; Julie Robotham; Alastair D Hay; Diana M Gibb; Mike Sharland;
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年(卷),期 2019(9),5
年度 2019
页码 e029875
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
community-acquired pneumonia antimicrobial resistance;

机译：社区获得性肺炎;抗菌素耐药性;

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1. Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial [J] . Carl Llor, Javier Arranz, Rosa Morros, BMC Family Practice . 2013,第1期

机译：大剂量口服青霉素与阿莫西林在社区内治疗成人非重症肺炎的疗效：一项随机对照试验的研究方案
2. Efficacy and safety of short duration azithromycin eye drops versus azithromycin single oral dose for the treatment of trachoma in children: a randomised, controlled, double-masked clinical trial. [J] . Cochereau I, Goldschmidt P, Goepogui A, British journal of ophthalmology . 2007,第5期

机译：短期阿奇霉素滴眼液与阿奇霉素单次口服剂量治疗儿童沙眼的疗效和安全性：一项随机对照双掩盖临床试验。
3. Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial [J] . Shally Awasthi British Medical Journal . 2004,第7443期

机译：阿莫西林治疗幼儿非严重肺炎的三天和五天治疗：一项多中心随机对照试验
4. THE EFFICACY AND DURATION OF IMMUNITY OF STELLAMUNE ONE ~RlA SINGLE DOSE MYCOPLASMA HYOPNEUMONIAE VACCINE FOR YOUNG PIGS [C] . A Dawson, S Thevasagayam, SC Smith, Congress of the International Pig Veterinary Society . 2002

机译：Stellamune One〜rla单剂量支原体支原体的疗效和持续时间为幼猪疫苗疫苗
5. Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial [O] . Carl Llor, Javier Arranz, Rosa Morros, 2013

机译：大剂量口服青霉素与阿莫西林在社区内治疗的成年人非重症肺炎的疗效：一项随机对照试验的研究方案
6. Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial [O] . Carl Llor, Javier Arranz, Rosa Morros, 2013

机译：大剂量口服青霉素与阿莫西林在社区内治疗的成年人非重症肺炎的疗效：一项随机对照试验的研究方案

Efficacy safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: a protocol for a randomIsed controlled Trial (CAP-IT)

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