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Evaluation of plasma microRNA-122 high-mobility group box 1 and keratin-18 concentrations to stratify acute gallstone disease: a pilot observational cohort study in an emergency general surgery unit

机译：血浆microRNA-122高迁移率族1和角蛋白18浓度对急性胆结石疾病分层的评估：在紧急普外科中的一项观察性队列研究

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ObjectiveTo obtain pilot data to evaluate the discriminatory power of biomarkers microRNA-122 (miR-122), high-mobility group box 1 (HMGB1), full-length keratin-18 (flk-18) and caspase-cleaved keratin-18 (cck-18) in plasma to identify potential biliary complications that may require acute intervention.

机译：目的获得试验数据以评估生物标志物microRNA-122（miR-122），高迁移率族框1（HMGB1），全长角蛋白18（flk-18）和半胱天冬酶裂解的角蛋白18（cck）的识别能力-18）在血浆中，以确定可能需要急性干预的潜在胆道并发症。

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期刊名称 BMJ Open
作者
Francesca Th’ng; Bastiaan Vliegenthart; Jonathan D Lea; Daniel J Antoine; James W Dear; Damian J Mole;
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作者单位

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年(卷),期 2018(8),4
年度 2018
页码 e020061
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
biochemistry gallstone disease microrna-122 HMGB-1 Keratin-18;

机译：生物化学;胆结石病;microrna-122;HMGB-1;角蛋白18;

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1. Plasma concentrations of high-mobility group box protein 1, soluble receptor for advanced glycation end-products and circulating DNA in patients with acute pancreatitis. [J] . Kocsis AK, Szabolcs A, Hofner P, Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] . 2009,第4期

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Evaluation of plasma microRNA-122 high-mobility group box 1 and keratin-18 concentrations to stratify acute gallstone disease: a pilot observational cohort study in an emergency general surgery unit

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