A comparative analysis of the particle size output of beclomethasone diproprionate salmeterol xinafoate and fluticasone propionate metered dose inhalers used with the Babyhaler Volumatic and Aerochamber spacer devices

摘要

AimsTo determine in vitro the effect of delay, inspiratory flow, and spacer washing on the drug output of metered dose inhalers (MDIs) used with different spacer devices.