Overexpression of Annexin A1 Suppresses Pro-InflammatoryFactors in PC12 Cells Induced by1-Methyl-4-Phenylpyridinium

摘要

Objective Annexin A1 (ANXA1) is suggested to have anti-inflammatory function. However, the precise function of ANXA1 has remained unclear. In this study, we therefore examined the potency of ANXA1 in regulating reactive oxygen species (ROS) production and suppressing pro-inflammatory responses in PC12 cells induced by 1-methyl-4-phenylpyridinium (MPP+).