首页> 美国卫生研究院文献>Cellular and Molecular Gastroenterology and Hepatology >Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling

【2h】

Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling

机译：促肾上腺皮质激素释放激素受体2在人类结肠癌中的表达减少通过持久性白介素6 / Stat3信号促进肿瘤生长和上皮向间充质转化。

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background & AimsChronic inflammation promotes development and progression of colorectal cancer (CRC). We explored the distribution of the corticotropin-releasing-hormone (CRH) family of receptors and ligands in CRC and their contribution in tumor growth and oncogenic epithelial-to-mesenchymal transition (EMT).

机译：背景与目的慢性炎症会促进结直肠癌（CRC）的发展和进程。我们探讨了促肾上腺皮质激素释放激素（CRH）受体和配体在CRC中的分布，以及它们在肿瘤生长和致癌性上皮-间质转化（EMT）中的作用。

著录项

期刊名称 Cellular and Molecular Gastroenterology and Hepatology
作者
Jorge A. Rodriguez; Sara Huerta-Yepez; Ivy Ka Man Law; Guillermina J. Baay-Guzman; Belen Tirado-Rodriguez; Jill M. Hoffman; Dimitrios Iliopoulos; Daniel W. Hommes; Hein W. Verspaget; Lin Chang; Charalabos Pothoulakis; Stavroula Baritaki;
展开▼
作者单位

展开▼
年(卷),期 2015(1),6
年度 2015
页码 610–630
总页数 21
原文格式 PDF
正文语种
中图分类免疫学;
关键词
Colorectal Cancer Inflammation Metastasis Neuropeptides;

机译：大肠癌;炎症;转移;神经肽;

相似文献

外文文献
中文文献
专利

1. KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers [J] . Chen Evan C., Karl Taylor A., Kalisky Tomer, Gastroenterology . 2015,第3期

机译：KIT信号促进小鼠结肠异种移植肿瘤的生长，并在人类结肠癌的子集中上调。
2. alpha-Hederin inhibits interleukin 6-induced epithelial-to-mesenchymal transition associated with disruption of JAK2/STAT3 signaling in colon cancer cells [J] . Sun Dongdong, Shen Weixing, Zhang Feng, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2018,第期

机译：α-hederin抑制白细胞介素6-诱导与结肠癌细胞中的JAK2 / Stat3信号传导的破坏相关的上皮 - 间充质转变
3. CRH promotes human colon cancer cell proliferation via IL-6/JAK2/STAT3 signaling pathway and VEGF-induced tumor angiogenesis [J] . Fang Xianjun, Hong Yali, Dai Li, Molecular Carcinogenesis . 2017,第11期

机译：CRH通过IL-6 / JAK2 / Stat3信号通路和VEGF诱导的肿瘤血管生成来促进人结肠癌细胞增殖
4. Flow cytometric monitoring of hormone receptor expression in human solid tumors [C] . Awtar Krishan Conference on Optical Diagnostics of Living Cells Ⅴ, Jan 23-25, 2002, San Jose, USA . 2002

机译：流式细胞仪监测人实体瘤中激素受体的表达
5. LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling. [D] . Lue, Hui-Wen. 2012

机译：LIV-1通过HB-EGF脱落和EGFR介导的ERK信号传导促进前列腺癌上皮到间质的转化和转移。
6. Toll Like Receptor 2 4 and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer [O] . Tanja Grimmig, Romana Moench, Jennifer Kreckel, 2016

机译：Toll样受体24和9信号促进人类胰腺癌的自调节肿瘤细胞生长和VEGF / PDGF表达。
7. Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling [O] . Rodriguez Jorge A., Huerta-Yepez Sara, Law Ivy Ka Man, 2015

机译：促肾上腺皮质激素释放激素受体2在人类结肠癌中的表达减少通过持久性白介素6 / Stat3信号促进肿瘤生长和上皮向间质转化。

Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling

摘要

著录项

相似文献

相关主题

期刊订阅