A Comparison of 1 Minimum Alveolar Concentration Desflurane and 1 Minimum Alveolar Concentration Isoflurane Anesthesia in Patients Undergoing Craniotomy for Supratentorial Lesions

摘要

BackgroundA critical point in craniotomy is during opening of the dura and the subsequent potential for cerebral edema. Use of desflurane in neurosurgery may be beneficial because it facilitates early postoperative neurologic evaluation; however, data on the effect of desflurane on intracranial pressure in humans are limited. Isoflurane has been used extensively in neurosurgical patients.