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Primary amelanotic malignant melanoma of the male urethra with inguinal lymph node metastasis successfully controlled by nivolumab: A case report

机译:尼古鲁单抗成功控制男性尿道原发性面色性恶性黑色素瘤腹股沟淋巴结转移

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摘要

We report a rare case of primary amelanotic malignant melanoma of the male urethra. A 65-year-old man with a urethral mass was referred to our hospital. A pathological diagnosis of a biopsy specimen revealed malignant melanoma. Thereafter, the patient underwent partial penectomy. The histopathological diagnosis was amelanotic malignant melanoma of the urethra. The patient had received DAV-Feron in an adjuvant setting; however, PET-CT revealed multiple metastasis. After receiving more than 10 cycles of nivolumab, the accumulation of FDG was no longer observed on PET-CT. The patient is currently free from recurrence at 20 months after nivolumab treatment.
机译:我们报告了男性尿道原发性无色素性恶性黑色素瘤的罕见病例。一名65岁的尿道积水男子被转诊到我们医院。活检标本的病理诊断显示为恶性黑色素瘤。此后,患者接受了部分切除术。组织病理学诊断为尿道黑素性恶性黑色素瘤。该患者在辅助治疗中接受了DAV-Feron;但是,PET-CT显示有多处转移。在接受超过10个周期的nivolumab循环后,在PET-CT上不再观察到FDG的积累。该患者目前在nivolumab治疗后20个月无复发。

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