Expression of bovine interleukin 15 and evaluation of its biological activity in vitro

摘要

Background/Aim:Recent studies have shown that interleukin-15 (IL-15)is a critical factor for the development and proliferation of CD8⁺ memory T cells. The aim of present study is to study the role bovine IL-15 (bIL-15)in activation pathway of bovine CD8⁺ T cells if any, which will be useful in designing the adjuvant to increase the duration of immunity of the vaccine preparations.