首页> 美国卫生研究院文献>Journal of Virology >Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect against Ocular Herpes Challenge

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Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect against Ocular Herpes Challenge

机译：基于人类无症状抗原决定簇肽/ CXCL10的初免/拉动疫苗可诱导单纯疱疹病毒特异的γ-干扰素-阳性CD107 + CD8 + T细胞浸润人源化HLA转基因兔的角膜和三叉神经节并抵抗眼疱疹攻击

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期刊名称 Journal of Virology
作者
Arif A. Khan; Ruchi Srivastava; Hawa Vahed; Soumyabrata Roy; Sager S. Walia; Grace J. Kim; Mona A. Fouladi; Taikun Yamada; Vincent T. Ly; Cynthia Lam; Anthony Lou; Vivianna Nguyen; Undariya Boldbaatar; Roger Geertsema; Nigel W. Fraser; Lbachir BenMohamed;
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作者单位

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年(卷),期 2018(92),16
年度 2018
页码 e00535-18
总页数 21
原文格式 PDF
正文语种
中图分类人体病毒学（致病病毒）;病毒（滤过性病毒）;
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外文文献

1. A Herpes Simplex Virus Type 1 Human Asymptomatic CD8(+) T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized'' HLA Transgenic Rabbit Model [J] . Srivastava Ruchi, Khan Arif A., Huang Jiawei, Investigative ophthalmology & visual science . 2015,第6期

机译：一种单纯型疱疹病毒1型人类无症状CD8（+）T细胞抗原决定基的疫苗可预防“人性化” HLA转基因兔模型中的眼疱疹。
2. A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a a??Humanizeda?? HLA Transgenic Rabbit Model [J] . Ruchi Srivastava, Arif A. Khan, Jiawei Huang, Investigative ophthalmology & visual science . 2015,第6期

机译：一种基于单纯疱疹病毒的1型无症状CD8 + T细胞抗原决定簇的疫苗可预防人疱疹病毒感染的眼疱疹。 HLA转基因兔模型
3. HLA-A02:01–Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpes [J] . Ruchi Srivastava, Arif A. Khan, Doran Spencer, The journal of immunology . 2015,第5期

机译：HLA-A02：01 –从单纯疱疹病毒外皮蛋白VP11 / 12中鉴定出的限制性抗原决定簇可以优先召回来自血清阳性无症状个体的多功能效应记忆CD8 + T细胞，并保护人源化HLA-A * 02：01转基因小鼠免受眼疱疹的侵害
4. A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a Humanized HLA Transgenic Rabbit Model [O] . Ruchi Srivastava, Arif A. Khan, Jiawei Huang, -1

机译：一种基于单纯型疱疹病毒的人类无症状CD8 + T细胞抗原决定簇的疫苗可在人源化 HLA转基因兔模型中预防眼疱疹
5. Asymptomatic HLA-A*02:01–Restricted Epitopes from Herpes Simplex Virus Glycoprotein B Preferentially Recall Polyfunctional CD8+T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice against Ocular Herpes [O] . Xavier Dervillez, Huma Qureshi, Aziz A. Chentoufi, 2013

机译：无症状HLA-A * 02：01疱疹病毒糖蛋白B的受限制表位，优先调查从血清阳性无症状个体的多官能CD8 + T细胞，并保护HLA转基因小鼠免受眼疱疹的影响

Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect against Ocular Herpes Challenge

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