Crystal structures of 2-(46-di­amino­pyrimidin-2-yl)sulfan­yl-N-(24-di­methyl­phen­yl)acetamide and 2-(46-di­amino­pyrimidin-2-yl)sulfan­yl-N-(3-meth­oxy­phen­yl)acetamide

摘要

In the title compounds, C14H17N5OS (I) and C13H15N5O2S (II), the dihedral angle between the pyrimidine and benzene rings is 58.64 (8)° in (I) and 78.33 (9)° in (II). In both compounds, there is an intra­molecular C—H⋯O hydrogen bond, and in (II) there is also an intra­molecular N—H⋯N hydrogen bond present. In the crystals of both compounds, a pair of N—H⋯N hydrogen bonds links the individual mol­ecules to form inversion dimers with R 2 ²(8) ring motifs. In (I), the dimers are linked by N—H⋯O and C—H⋯O hydrogen bonds, enclosing R 2 ¹(14), R 2 ¹(11) and R 2 ¹(7) ring motifs, forming layers parallel to the (100) plane. There is also an N—H⋯π inter­action present within the layer. In (II), the inversion dimers are linked by N—H⋯O hydrogen bonds enclosing an R 4 ⁴(18) ring motif. The presence of N—H⋯O and C—H⋯O hydrogen bonds generate an R 2 ¹(6) ring motif. The combination of these various hydrogen bonds results in the formation of layers parallel to the (1-11) plane.