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Phase II study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor study

机译：伊立替康联合替莫唑胺（TEMIRI）治疗复发性或难治性髓母细胞瘤患儿的II期临床研究：联合ITCC和SIOPE脑肿瘤研究

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BackgroundThis multicenter phase II study investigated temozolomide + irinotecan (TEMIRI) treatment in children with relapsed or refractory medulloblastoma.

机译：背景这项多中心II期研究调查了替莫唑胺+伊立替康（TEMIRI）在复发或难治性髓母细胞瘤儿童中的治疗方法。

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期刊名称 Neuro-Oncology
作者
Jacques Grill; Birgit Geoerger; Lyle Gesner; Danuta Perek; Pierre Leblond; Adela Cañete; Isabelle Aerts; Luis Madero; Josep Sanchez de Toledo Codina; Joris Verlooy; Edward Estlin; Laura Cisar; Aurora Breazna; Andrew Dorman; Simon Bailey; Gary Nicolin; Richard G. Grundy; Darren Hargrave;
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年(卷),期 2013(15),9
年度 2013
页码 1236–1243
总页数 8
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
关键词
medulloblastoma temozolomide TEMIRI;

机译：髓母细胞瘤;替莫唑胺;TEMIRI;

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专利

1. Phase Ⅱ study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor study [J] . Jacques Grill, Birgit Geoerger, Lyle Gesner, Neuro-Oncology . 2013,第9期

机译：伊立替康联合替莫唑胺（TEMIRI）治疗复发性或难治性髓母细胞瘤患儿的Ⅱ期临床研究：ITCC和SIOPE联合研究
2. A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: A joint ITCC and SIOPE-brain tumour study [J] . HargraveD., GeoergerB., FrappazD., Journal of neuro-oncology. . 2013,第1期

机译：伊立替康联合替莫唑胺（TEMIRI）在新诊断的高级别神经胶质瘤患儿中的II期单臂研究：联合的ITCC和SIOPE-脑肿瘤研究
3. Dose-Finding Study of Vinblastine in Combination with Nilotinib in Patients with Refractory or Recurrent Low-Grade Glioma: Results of the Itcc/Siope-Brain Vinilo Phase I Trial (NCT01887522) [J] . Grill J., Le Deley M. C., Gwenael L. T., Pediatric blood & cancer . 2016,第Suppla3期

机译：长春碱与尼洛替尼联合用于难治性或复发性低度胶质瘤患者的剂量发现研究：Itcc / Siope-Brain Vinilo I期试验结果（NCT01887522）
4. CLINICAL STUDIES OF PHOTODYNAMIC THERAPY FOR MALIGNANT BRAIN TUMORS: Karnofsky score and neurological score in patients with recurrent gloms treated with Photofrin-PDT [C] . P. Muller, B. Wilson, L. Lilge, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy Ⅺ Jan 19-20, 2002 San Jose, USA . 2002

机译：光敏疗法治疗恶性脑肿瘤的临床研究：Photofrin-PDT治疗复发性胶质瘤患者的卡氏评分和神经系统评分
5. A phase I study of vincristine, escalating doses of irinotecan, temozolomide and bevacizumab (VIT-B) in pediatric and adolescent patients with recurrent or refractory solid tumors of non-hematopoietic origin [D] . Venkatramani, Rajkumar. 2010

机译：长春新碱，伊非替康，替莫唑胺和贝伐单抗（VIT-B）逐步剂量在患有非造血源性复发或难治性实体瘤的儿童和青少年患者中的I期研究
6. EPT-01DOSE-FINDING STUDY OF VINBLASTINE IN COMBINATION WITH NILOTINIB IN CHILDREN ADOLESCENTS AND YOUNG ADULTS WITH REFRACTORY OR RECURRENT LOW-GRADE GLIOMA: RESULTS OF THE ITCC/SIOPE-BRAIN VINILO PHASE I TRIAL (NCT01887522) [O] . Jacques Grill, Marie-Cecile Le Deley, Gwenael Le Teuff, 2016

机译：EPT-01定量研究长春花碱与尼洛替尼联合用于顽固性或复发性低级胶质瘤的儿童青少年和年轻成人：ITCC / SIOPE-BRAIN VININILO I阶段试验（NCT01887522）
7. Phase II Study of Irinotecan and Temozolomide in Children With Relapsed or Refractory Neuroblastoma: A Children's Oncology Group Study [O] . Bagatell, Rochelle, London, Wendy B., Wagner, Lars M., 2011

机译：伊立替康和替莫唑胺在儿童复发或难治性神经母细胞瘤的II期研究：儿童肿瘤学组研究

Phase II study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor study

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