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Association of known common genetic variants with primary open angle primary angle closure and pseudoexfoliation glaucoma in Pakistani cohorts

机译:巴基斯坦人群中已知的常见遗传变异与原发性开角原发性闭角和假性剥脱性青光眼的关联

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摘要

PurposeDespite the different etiology of primary open angle glaucoma (POAG), primary angle closure glaucoma (PACG), and pseudoexfoliative glaucoma (PEXG), several studies have suggested that these forms of glaucoma have overlapping genetic risk factors. Therefore, the aim of this study was to evaluate the role of genetic variants recently associated with POAG in different types of glaucoma in Pakistani POAG, PACG, and PEXG patient cohorts.
机译:目的尽管原发性开角型青光眼(POAG),原发性闭角型青光眼(PACG)和假性剥脱性青光眼(PEXG)的病因不同,但多项研究表明这些形式的青光眼具有重叠的遗传危险因素。因此,本研究的目的是评估巴基斯坦POAG,PACG和PEXG患者队列中最近与POAG相关的遗传变异在不同类型的青光眼中的作用。

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