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Safety Assessment of Mainstream Smoke of Herbal Cigarette

机译:草本卷烟主流烟气安全性评价

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摘要

Owing to the increase in price of cigarettes in Korea, herbal cigarettes have received increasing attention as a non-smoking aid; however, its safety has hardly been studied. We analyzed some of the toxic components in the mainstream smoke of herbal cigarettes, performed a mutagenicity test on smoke condensates for safety assessment, and compared the results with the corresponding values of a general cigarette with the same tar content. Herbal cigarette “A” was smoked using automatic smoking machine under ISO conditions in a manner similar to general cigarette “T”. The tar content measured was higher than that inscribed on the outside of a package. The mainstream smoke of herbal cigarette “A” did not contain detectable levels of tobacco-specific nitrosamines and nicotine. Carbon monoxide and benzo(α)pyrene contents in herbal cigarette “A” were higher than those in the general cigarette “T”. The phenolic contents such as hydroquinone, resorcinol, and catechol in herbal cigarette “A” were higher than those in the general cigarette “T”, but cresol contents in herbal cigarette “A” were lower than those in the general cigarette “T”. The content of aromatic amines such as 4-aminobiphenyl in herbal cigarette “A” was higher than that in the general cigarette “T”; however, this difference was not statistically significant. On the other hand, 1-aminonaphthalene, 2-aminonaphthalene, and 3-aminobiphenyl contents in herbal cigarette “A” were lower than those in the general cigarette “T”. The smoke condensates of herbal cigarette “A” exhibited a higher mutagenic potential than the condensates from the general cigarette “T” at the same concentration. We concluded that the mainstream smoke of herbal cigarette contains some toxic components, the smoke condensates of herbal cigarettes are mutagenic similar to general cigarette because of combustion products, and that the evaluation of the chemical and biological safety of all types of herbal cigarettes available on the market.
机译:由于韩国卷烟价格的上涨,草药卷烟作为一种非吸烟辅助手段受到了越来越多的关注。但是,其安全性尚未得到研究。我们分析了草药卷烟主流烟气中的一些有毒成分,对烟气冷凝物进行了诱变性测试以进行安全性评估,并将结果与​​具有相同焦油含量的普通卷烟的相应值进行了比较。使用自动吸烟机在ISO条件下以类似于普通卷烟“ T”的方式吸烟“ A”卷烟。测得的焦油含量高于包装外部标明的焦油含量。草药卷烟“ A”的主流烟气中没有检测到水平的烟草特有的亚硝胺和尼古丁。草药卷烟“ A”中的一氧化碳和苯并(α)py含量高于普通卷烟“ T”中的含量。草本卷烟“ A”中的对苯二酚,间苯二酚和邻苯二酚等酚类含量高于普通卷烟“ T”中的含量,而草药卷烟“ A”中的甲酚含量却低于普通卷烟“ T”中的甲酚含量。草药卷烟“ A”中的4-氨基联苯等芳香胺的含量高于普通卷烟“ T”中的;但是,这种差异在统计上并不显着。另一方面,草药卷烟“ A”中的1-氨基萘,2-氨基萘和3-氨基联苯的含量低于普通卷烟“ T”中的含量。与相同浓度的普通香烟“ T”的冷凝物相比,草药香烟“ A”的烟雾冷凝物具有更高的诱变潜力。我们得出的结论是,草药香烟的主流烟气中含有一些有毒成分,由于燃烧产物,其与普通香烟的烟雾冷凝物具有相似的致突变性,并且评估了市场上所有类型的草药香烟的化学和生物安全性市场。

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