Performance of the 13C-urea breath test for the diagnosis of H. pylori infection using a substrate synthesized in Brazil: A preliminary study

摘要

OBJECTIVE:The ¹³C-urea breath test is the main non-invasive test for the diagnosis of Helicobacter pylori infection. The availability of this test throughout the country is limited, mainly due to the difficulty in obtaining the labeled isotope from abroad. Recently, researchers from the Nuclear Energy Center in Agriculture at the University of São Paulo (CENA/USP) succeeded in synthesizing ¹³C-enriched urea for Helicobacter pylori diagnosis. The aim of the study was to compare the performance of the ¹³C-urea breath test using ¹³C-urea acquired abroad with that of a test using ¹³C-urea synthesized in Brazil.