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nab-Paclitaxel/carboplatin in elderly patients with advanced squamous non-small cell lung cancer: a retrospective analysis of a Phase III trial

机译：nab-紫杉醇/卡铂治疗老年晚期鳞状非小细胞肺癌的患者：III期临床试验的回顾性分析

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BackgroundLimited data on elderly patients with squamous advanced non-small cell lung cancer (NSCLC) preclude optimal treatment. Here, we report the outcomes of a retrospective analysis of a subset of patients ≥70 years with squamous histology from the Phase III trial that evaluated nab-paclitaxel/carboplatin vs paclitaxel/carboplatin.

机译：背景老年晚期鳞状非小细胞肺癌（NSCLC）患者的有限数据排除了最佳治疗方法。在这里，我们报告了一项III期临床试验的回顾性分析结果，该研究是对70岁以上鳞癌的一部分患者进行回顾性分析，该试验评估了nab-紫杉醇/卡铂与紫杉醇/卡铂的关系。

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期刊名称 Drug Design Development and Therapy
作者
Cesare Gridelli; Tianlei Chen; Amy Ko; Mary E O’Brien; Teng Jin Ong; Mark A Socinski; Pieter E Postmus;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 1445–1451
总页数 7
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词
taxanes comorbidities age chemotherapy histology;

机译：紫杉烷类;合并症;年龄;化学疗法;组织学;

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专利

1. nab-Paclitaxel/carboplatin in elderly patients with advanced squamous non-small cell lung cancer: a retrospective analysis of a Phase III trial [J] . Cesare Gridelli, Tianlei Chen, Amy Ko, Drug Design, Development and Therapy . 2018,第4期

机译：nab-紫杉醇/卡铂治疗老年晚期鳞状非小细胞肺癌的患者：III期临床试验的回顾性分析
2. P2.03a-028 Phase I/II Trial of Carboplatin, nab-Paclitaxel and Bevacizumab for Advanced Non-Squamous Non-Small Cell Lung Cancer: Results of Phase I Part [J] . Satoshi Ikeo, Naoyuki Nogami, Hiromoto Kitajima, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2017,第1期

机译：P2.03A-028 Carboplatin，Nab-Paclitaxel和Bevacizumab的A期I / II试验用于高级非鳞状非小细胞肺癌：I阶段的结果
3. P2.03a-028 Phase I/II Trial of Carboplatin, nab-Paclitaxel and Bevacizumab for Advanced Non-Squamous Non-Small Cell Lung Cancer: Results of Phase I Part [J] . Satoshi Ikeo, Naoyuki Nogami, Hiromoto Kitajima, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2017,第1期

机译：P2.03A-028 Carboplatin，Nab-Paclitaxel和Bevacizumab的A期I / II试验用于高级非鳞状非小细胞肺癌：I阶段的结果
4. Pemetrexed versus docetaxel single agent chemotherapy in chemotherapy-naive elderly patients with advanced non-small cell lung cancer [C] . Hua Xin, Zhenguo Han, Haibo Huang 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：培美曲塞与多西他赛单药化疗在未接受化疗的老年晚期非小细胞肺癌患者中的作用
5. Evaluation of Symptom Management in Patients with Advanced Stage (IIIB and IV) Non-Small Cell Lung Cancer [D] . Mann, LaTonya E. 2018

机译：晚期（IIIB和IV）非小细胞肺癌患者症状管理的评估
6. Elderly Subset Analysis of Randomized Phase III Study Comparing Pemetrexed Plus Carboplatin with Docetaxel Plus Carboplatin as First-Line Treatment for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer [O] . José Rodrigues Pereira, Rebecca Cheng, Mauro Orlando, -1

机译：培美曲塞加卡铂与多西他赛加卡铂作为一线治疗局部晚期或转移性非小细胞肺癌患者的随机III期研究的老年人亚组分析
7. nab-Paclitaxel/carboplatin in elderly patients with advanced squamous non-small cell lung cancer: a retrospective analysis of a Phase III trial [O] . Cesare Gridelli, Tianlei Chen, Amy Ko, 2018

机译：NAB-PACLITAXEL / CARBOPOLATIN在老年鳞状非小细胞肺癌患者中：回顾性分析III期试验

nab-Paclitaxel/carboplatin in elderly patients with advanced squamous non-small cell lung cancer: a retrospective analysis of a Phase III trial

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