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Pituitary magnetic resonance imaging predictive role in the therapeutic response of growth hormone-secreting pituitary adenomas

机译:垂体磁共振成像在生长激素分泌性垂体腺瘤治疗反应中的预测作用

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摘要

BackgroundGrowth hormone (GH)-secreting pituitary adenomas, responsible for the development of acromegaly, are the second most frequent type of secreting pituitary adenomas and are characterized by very variable T2-weighted signal intensity on pituitary magnetic resonance imaging (MRI). Previous data have demonstrated a correlation between T2-weighted tumor signal intensity and response to therapy with conventional somatostatin analogs (SSA) in patients with acromegaly. The aim of the current retrospective study was to investigate the correlation between the T2-weighted tumor signal on pituitary MRI and both biochemical and radiological response to first-line SSA therapy.
机译:背景分泌促生长激素(GH)的垂体腺瘤是肢端肥大症的发展原因,是分泌垂体腺瘤的第二常见类型,其特征是垂体磁共振成像(MRI)的T2加权信号强度变化很大。先前的数据表明,肢端肥大症患者的T2加权肿瘤信号强度与常规生长抑素类似物(SSA)对治疗的反应之间存在相关性。当前回顾性研究的目的是研究垂体MRI上的T2加权肿瘤信号与对一线SSA治疗的生化和放射学反应之间的相关性。

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