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Prognostic utility of coronary computed tomographic angiography

机译:冠状动脉计算机断层血管造影术的预后效用

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摘要

Coronary computed tomographic angiography (CCTA) employing CT scanners of 64-detector rows or greater represents a noninvasive method that enables accurate detection and exclusion of anatomically obstructive coronary artery disease (CAD), providing excellent diagnostic information when compared to invasive angiography. There are numerous potential advantages of CCTA beyond simply luminal stenosis assessment including quantification of atherosclerotic plaque volume as well as assessment of plaque composition, extent, location and distribution. In recent years, an array of studies has evaluated the prognostic utility of CCTA findings of CAD for the prediction of major adverse cardiac events, all-cause death and plaque instability. This prognostic information enhances risk stratification and, if properly acted upon, may improve medical therapy and/or behavioral changes that may enhance event-free survival. The goal of the present article is to summarize the current status of the prognostic utility of CCTA findings of CAD.
机译:采用64排或更多排CT扫描仪的冠状动脉计算机断层血管造影术(CCTA)代表了一种非侵入性方法,能够准确地检测和排除解剖学上阻塞性冠状动脉疾病(CAD),与侵入性血管造影术相比可提供出色的诊断信息。 CCTA除了简单的腔狭窄评估外,还有许多潜在优势,包括动脉粥样硬化斑块体积的量化以及斑块组成,程度,位置和分布的评估。近年来,一系列研究评估了CCTA的CAD预后在预测重大不良心脏事件,全因死亡和斑块不稳定性方面的预后效用。该预后信息可增强风险分层,如果采取适当措施,则可改善药物治疗和/或行为改变,从而可提高无事件生存率。本文的目的是总结CCTA的CAD预后的实用性。

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