The Efficacy of Carotenoids in DNA Repair in Lung Cancer

摘要

To explore the efficacy and mechanism of β-carotene, lycopene, and β-cryptoxanthin, three major carotenoids in cigarette smoking-induced oxidative DNA damage in lung carcinoma cells. We hypothesize that carotenoids reverse cigarette smoke-induced DNA lesions and genotoxic events, thereby playing a role in modulating genome stability.