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Blood lead levels in children and pregnant women living near a lead-reclamation plant.

机译:生活在铅回收厂附近的儿童和孕妇的血铅水平。

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摘要

OBJECTIVE: To determine the effect of lead contamination around a lead-reclamation plant on the blood lead levels of children and pregnant women living in the area. DESIGN: Prevalence study. SETTING: Residents living 150 m or less (high-exposure area), 151 to 400 m (intermediate-exposure area) or 401 to 800 m (low-exposure area) southeast from the plant. PARTICIPANTS: All children aged 10 years or less and all pregnant women living in the designated area. OUTCOME MEASURES: Correlation of venous blood lead levels with soil lead concentrations in the areas in which the subjects lived and with sociodemographic and behavioural factors. MAIN RESULTS: Of the estimated 57 pregnant women 38 (67%) participated: 20 were in the high-exposure area and 18 in the other two areas; their geometric mean blood lead levels were low (0.15 and 0.13 mumol/L respectively). Of the 625 eligible children 510 (82%) participated: 169 were in the high-exposure area, 179 in the intermediate-exposure area and 162 in the low-exposure area; their geometric mean lead levels were 0.43, 0.30 and 0.26 mumol/L respectively. Within each age group children in the high-exposure area had the highest levels. The mean levels for children aged 6 months to 5 years were 0.49, 0.35 and 0.28 mumol/L in the three areas respectively. Within each exposure group children aged 1 to 2 years had the highest levels. No potential confounding variables could explain the relation between blood lead level and soil lead concentration. CONCLUSIONS: The pregnant women's blood lead levels did not seem to be affected by exposure level, but the children's levels were primarily related to the soil lead concentration.
机译:目的:确定铅回收厂周围的铅污染对居住在该地区的儿童和孕妇的血铅水平的影响。设计:患病率研究。地点:居住在植物东南方150 m以下(高暴露区域),151至400 m(中暴露区域)或401至800 m(低暴露区域)的居民。参加者:所有10岁或以下的儿童以及所有居住在指定区域的孕妇。观察指标:受试者所在地区的静脉血铅水平与土壤铅浓度以及社会人口统计学和行为因素的相关性。主要结果:在估计的57名孕妇中,有38名(67%)参加了调查:20名在高暴露地区,18名在其他两个地区。其几何平均血铅水平较低(分别为0.15和0.13 mumol / L)。在625名合格儿童中,有510名(82%)参加了该项目:高暴露区169人,中暴露区179人,低暴露区162人;其几何平均铅含量分别为0.43、0.30和0.26 mumol / L。在每个年龄段中,高暴露地区的儿童的水平最高。三个地区6个月至5岁儿童的平均水平分别为0.49、0.35和0.28μmol/ L。在每个接触组中,年龄在1-2岁的儿童具有最高水平。没有潜在的混淆变量可以解释血铅水平与土壤铅浓度之间的关系。结论:孕妇的血铅水平似乎不受暴露水平的影响,但儿童的血铅水平主要与土壤铅浓度有关。

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