Binding characteristics of 3H-JSM10292: a new cell membrane-permeant non-peptide bradykinin B2 receptor antagonist

摘要

BACKGROUND AND PURPOSEA ³H-labelled derivative of the novel small-molecule bradykinin (BK) B2 receptor antagonist JSM10292 was used to directly study its binding properties to human and animal B2 receptors in intact cells and to closely define its binding site.