首页> 美国卫生研究院文献>British Heart Journal >Prognostic significance of electrocardiographic findings in angina at rest. Therapeutic implications.
【2h】

Prognostic significance of electrocardiographic findings in angina at rest. Therapeutic implications.

机译:心电图检查对静息型心绞痛的预后意义。治疗意义。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Ninety-five patients with angina at rest were observed in the coronary care unit. Eighty-one per cent presented concomitantly or had previously presented some other manifestations of coronary artery disease. These patients were divided into two subgroups. In subgroup 1 (40 patients), episodes of non-exertional angina were associated with a pattern of hyperacute subepicardial injury and, frequently, with ventricular arrhythmias. In subgroup 2 (55 patients), the episodes of angina at rest were attended by horizontal ST depression, isolated T wave inversion, or trivial ST-T changes. Coronary angiographic findings were similar in both subgroups. Symptoms regressed in only 9% of patients in subgroup 1 while they were receiving beta-receptor antagonists, whereas amiodarone alone or amiodarone with nifedipine was successful in 58%. Of these patients, 25% developed a myocardial infarction shortly after admission. In subgroup 2 patients, beta-blockers were successful in 61%. Amiodarone isolated or associated with nifedipine was successful in 55% of the patients in whom it was tried. Only 5% of patients in this subgroup developed a myocardial infarction during their hospital stay. It is concluded that: (1) observation of the electrocardiogram during spontaneous angina in patients with known atherosclerotic coronary heart disease may be of prognostic significance and may influence therapeutic decision. (2) Amiodarone by virtue of its anginal and antiarrhythmic properties may be particularly useful in the treatment of non-exertional angina.
机译:在冠心病监护室中观察到95名静息型心绞痛患者。 81%的患者同时出现或以前出现过冠状动脉疾病的其他表现。这些患者分为两个亚组。在亚组1(40例患者)中,非劳累性心绞痛发作与超急性心外膜下损伤模式有关,并经常伴有室性心律失常。在亚组2(55例患者)中,静息型心绞痛发作时伴有水平ST压低,孤立的T波倒置或琐碎的ST-T改变。在两个亚组中,冠状动脉造影结果相似。在接受β受体拮抗剂治疗的亚组1中,只有9%的患者出现症状消退,而单独使用胺碘酮或使用硝苯地平的胺碘酮则有58%成功。这些患者中,有25%在入院后不久出现心肌梗塞。在亚组2的患者中,β受体阻滞剂成功的占61%。硝苯地平分离或与硝苯地平联用的胺碘酮在尝试使用它的55%的患者中成功。在该亚组中,只有5%的患者在住院期间发生了心肌梗塞。结论:(1)已知动脉粥样硬化性冠心病患者自发性心绞痛的心电图观察可能具有预后意义,并可能影响治疗决策。 (2)胺碘酮由于其心绞痛和抗心律不齐的特性,在非劳累性心绞痛的治疗中可能特别有用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号