The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury

机译：加米金海棠对急性肺损伤动物模型中弹性蛋白酶/脂多糖诱导的肺部炎症的影响

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摘要

BackgroundGamijinhae-tang (GJHT) has long been used in Korea to treat respiratory diseases. The therapeutic effect of GJHT is likely associated with its anti-inflammatory activity. However, the precise mechanisms underlying its effects are unknown. This study was conducted to evaluate the protective effects of GJHT in a porcine pancreatic elastase (PPE) and lipopolysaccharide(LPS) induced animal model of acute lung injury (ALI).

机译：背景Gamijinhae-tang（GJHT）在韩国长期以来一直用于治疗呼吸系统疾病。 GJHT的治疗作用可能与其抗炎活性有关。但是，其作用的确切机制尚不清楚。进行这项研究以评估GJHT对猪胰腺弹性蛋白酶（PPE）和脂多糖（LPS）诱导的急性肺损伤（ALI）动物模型的保护作用。

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期刊名称 BMC Complementary and Alternative Medicine
作者
Sung-Hwa Sohn; HaRyeon Jang; Youngeun Kim; Young Pyo Jang; Seung-Hun Cho; Heejae Jung; Sungki Jung; Hyunsu Bae;
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年(卷),期 2013(13),-1
年度 2013
页码 176
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
ALI COPD Gamijinhae-tang Elastase IL-6 IL-1β Goblet cell;

机译：ALI;COPD;Gamijinhae-tang;弹性蛋白酶;IL-6;IL-1β;杯状细胞;

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专利

1. The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury [J] . Sung-Hwa Sohn, HaRyeon Jang, Youngeun Kim, BMC Complementary and Alternative Medicine . 2013,第1期

机译：Gamijinhae-tang对急性肺损伤动物模型中弹性蛋白酶/脂多糖诱导的肺部炎症的影响
2. Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats. [J] . Tao Yang, Junjie Zhang, Lulu Sun, Inflammation research: Official journal of the European Histamine Research Society . 2012,第6期

机译：中性粒细胞弹性蛋白酶抑制剂（依格司他钠）和自由基清除剂（依达拉奉）对脂多糖诱导的大鼠急性肺损伤的联合作用。
3. Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats [J] . Tao Yang, Junjie Zhang, Lulu Sun, Inflammation Research . 2012,第6期

机译：中性粒细胞弹性蛋白酶抑制剂（双降司他钠）和自由基清除剂（依达拉奉）对脂多糖诱导的大鼠急性肺损伤的联合作用
4. Activation of nuclear factor-kappa B (NF-kB) in alveolar macrophages and lung tissue of ventilated animals with acute lung injury. [C] . Acta pharmacologica sinica . 2002

机译：急性肺损伤通气动物肺泡巨噬细胞和肺组织中核因子-κB（NF-kB）的活化。
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation [O] . Hong Yao, Yiping Sun, Shasha Song, 2017

机译：薯os素通过抑制氧化应激和炎症反应对脂多糖诱导的急性肺损伤的保护作用
7. The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury [O] . 2013

机译：加米金海棠对急性肺损伤动物模型中弹性蛋白酶/脂多糖诱导的肺部炎症的影响
8. Acute Lung Injury Following Smoke Inhalation: Predictive Value of Sputum Biomarkers and Time Course of Lung Inflammation [R] . Burgess, J. L. 2007

机译：吸烟后急性肺损伤：痰标本生物标志物的预测价值和肺部炎症的时间过程

The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury

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