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A Sequential Study of Age-Related Lipofuscin Accumulation in Hippocampus and Striate Cortex of Rats

机译：大鼠海马和纹状体皮质中与年龄有关的脂褐素积累的序贯研究

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BackgroundThe age-pigment, lipofuscin that accumulates in cells intrinsically and progressively with age is considered as the hallmark of aging. This accumulation is more prominent in post-mitotic cells like neurons and also appears in glia.

机译：背景技术随着年龄的增长，在体内逐渐积累的年龄色素脂褐素被认为是衰老的标志。这种积累在有丝分裂后的细胞（如神经元）中更为明显，也出现在神经胶质细胞中。

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期刊名称 Annals of Neurosciences
作者
Sarika Singh Kushwaha; Nisha Patro; Ishan Kumar Patro;
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年(卷),期 2018(25),4
年度 2018
页码 223–233
总页数 11
原文格式 PDF
正文语种
中图分类神经科学;
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1. Transient accumulation of Gallyas-Braak-positive and phosphorylated tau-immunopositive substances in neuronal lipofuscin granules in the amygdala, hippocampus and entorhinal cortex of rats during long-term chloroquine intoxication [J] . I. Takeuchi, Y. Takeuchi Acta Neuropathologica . 2001,第2期

机译：长期氯喹中毒后大鼠杏仁核，海马和内嗅皮层神经元脂褐素颗粒中Gallyas-Braak阳性和磷酸化tau免疫阳性物质的短暂积累
2. Age-associated alterations of lipofuscin, membrane-bound ATPases and intracellular calcium in cortex, striatum and hippocampus of rat brain: protective role of glutathione monoester. [J] . Murali G, Panneerselvam KS, Panneerselvam C International journal of developmental neuroscience: the official journal of the International Society for Developmental Neuroscience . 2008,第2期

机译：鼠脑皮质，纹状体和海马中脂褐素，膜结合ATP酶和细胞内钙的年龄相关变化：谷胱甘肽单酯的保护作用。
3. Sequential histochemical studies of neuronal lipofuscin in human cerebral cortex from the first to the ninth decade of life. [J] . Benavides SH, Monserrat AJ, Farina S, Archives of Gerontology and Geriatrics: An International Journal Integrating Experimental, Clinical and Social Studies on Ageing . 2002,第3期

机译：从生命的第一个十年到第九个十年，对人类大脑皮层神经元脂褐素的顺序组织化学研究。
4. Longitudinal Study of Chronic Stress Induced Electrophysiological Alterations in Pre-Frontal Cortex, Ventral and Dorsal Hippocampus in Freely Moving Rodents [C] . L.R. Jacinto, J.S. Reis, N.S. Dias, World Congress on Medical Physics and Biomedical Engineering . 2013

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5. A Translational Approach to Enzyme-Mediated Retinal Lipofuscin Removal for Atrophic Age-Related Macular Degeneration and Stargardt's Disease [D] . Moody, Kelsey James. 2019

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6. Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease [O] . Valérie Fontaine, Elodie Monteiro, Mylène Fournié, 2020

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7. Effects of Late-Life Caloric Restriction on Age-Related Alterations in the Rat Cortex and Hippocampus [O] . Claudia Tonini, Marco Segatto, Francesca Martino, 2021

机译：晚生热量限制对大鼠皮质和海马年龄相关变化的影响

A Sequential Study of Age-Related Lipofuscin Accumulation in Hippocampus and Striate Cortex of Rats

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