机译
p16染色作为人类乳头瘤病毒(HPV)状态在细针抽吸物和颈部淋巴结转移的核心活检物中的替代标志物的保真度:对HPV测试方案的影响
摘要:ObjectivesThe importance of detecting human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) has resulted in a growing expectation for HPV testing of clinical samples. Although testing protocols vary, most pertain to primary tumor biopsies/resections. Testing of fine needle aspirates and core biopsies (FNACB) is advantageous, but it is unclear whether technical and biologic factors adversely affect the fidelity of HPV detection in these samples.