后颅窝容积大小与原发三叉神经痛的相关性研究

摘要

目的 研究原发性三叉神经痛患者后颅窝容积的大小与其发病的相关性.方法 回顾性分析2013年9月至2015年9月经微血管减压术(MVD)治疗原发性三叉神经痛患者68例的术前MRI,并征集50例健康志愿者行MRI检查;对MRI图像进行后颅窝形态学测量,比较二者大小差异.结果 通过对MRI进行进一步测量分析后发现,三叉神经痛患者的后颅窝容积较小,受累的三叉神经有一定程度的萎缩,差异具有统计学意义(P<0.05).结论 后颅窝狭小导致原发性三叉神经痛患病率的增加.%Objective To study the relationship between the size of posterior cranial fossa and its incidence in patients with primary trigeminal neuralgia.Methods A retrospective analysis was performed on the treatment of menstrual MVD for primary trigeminal neuralgia in 68 patients with preoperative MRI from September, 2013 to September, 2015,and data of 50 healthy volunteers undergoing MRI examination were collected;measurement on the morphology of cranial fossa MRI image,the size difference between the two.Results After further measurement and analysis of MRI,it was found that the posterior fossa volume of the patients with trigeminal neuralgia was small,and the involvement of the trigeminal nerve had a certain degree of atrophy,and the difference was statistically significant(P<0.05).Conclusions The increase of the incidence of primary trigeminal neuralgia is caused by the small posterior fossa.