首页> 中文期刊>世界核心医学期刊文摘:心脏病学分册 >1970—1974年与1990—1994年两个时期之间一个特定老年人群中心力衰竭发病率和存活率的变化

1970—1974年与1990—1994年两个时期之间一个特定老年人群中心力衰竭发病率和存活率的变化

     

摘要

Background -An epidemic increase in heart failure(HF) mortality, hospitalization, and prevalence rates has been observed among older persons in recent years. It is unclear whether this reflects an increase in incidence or survival. Methods and Results -We conducted a retrospective cohort study comparing HF in 1970 to 1974 and 1990 to 1994 among persons ≥65 years old belonging to a large, well-defined population with complete medical records available for research. Using Framingham clinical criteria, we identified incident cases of HF in the respective periods. Age-specific and age-adjusted incidence, mortality, and survival rates were compared. Cox proportional-hazards models were used to assess association of comorbidities and medications with survival. During 38 800 and 127 419 person-years for 1970 to 1974 and 1990 to 1994, respectively, 387 and 1555 confirmed incident cases were identified. When adjusted for age, incidence increased by 14%(95%CI 2%to 28%). Increased incidence tended to be greater for older persons and for men. Based on 5-year follow-up and adjustment for age and comorbidities, the mortality hazards decreased 33%(95%CI 14%to 48%) among men and 24%(95%CI-1%to 43%) among women. Conclusions -The epidemic increase in HF among the older population between the 1970s and 1990s is associated with increased incidence and improved survival, with both of these effects being greater in men.

著录项

相似文献

  • 中文文献
  • 外文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号