Higher baseline pattern standard deviation (PSD) and larger vertical cup to disk ratio (VC/D) were factors in the predictive model for the development of pr imary open angle glaucoma (POAG) in the Ocular Hypertension Treatment Study. Be cause early changes in PSD and VC/D may be indicative of early POAG damage, we r epeated the prediction model excluding PSD and VC/D. Reanalysis of baseline fact ors for the development of POAG. We compared the hazard ratios for baseline fact ors predictive of POAG in the multivariate Cox proportional hazards model that i ncluded PSD and VC/D and in the model that excluded them. Hazard ratios for base line factors predictive of POAG in Ocular Hypertension Treatment Study were not substantially affected by the inclusion or exclusion of PSD and VC/D in the prop ortional hazards model. Whether PSD or VC/D was included in the Cox proportional hazards model, the same baseline factors were statistically significant and the ir hazard ratios were essentially similar.
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