Aims: To characterise changes in ocular dimensions after combined cataract ope ration and trabeculectomy with mitomycin C using separate incisions (combined op eration). Methods: 24 consecutive eyes that had combined operation and 16 eyes t hat had cataract operation alone were enrolled. The axial lengths before and aft er operations were determined with non-contact optical coherence biometry. The intraocular pressures (IOP), axial lengths, corneal curvatures, and the expected and observed refractive errors before and after operations were compared. Resul ts: After a combined operation, mean IOP was significantly reduced from 16.6 (SD 5.8) mm Hg to 10.9 (4.1)mm Hg (p < 0.00001), and mean axial lengthwas significa ntly shortened from 24.10 (0.98) mm to 23.98 (0.96) mm (p < 0.00001). The mean a xial length reduction after combined operation (117 (57)-μm) was significantly larger than the reduction after cataract operation alone (75 (38) p< 0.02), and correlated significantly with the postoperative IOP (p< 0.002). There was a mea n with the rule surgically induced corneal astigmatism of 0.44 (0.83)-dioptre b y vector analysis, and a significant increase of mean keratometry reading of 0.2 3 (0.46) dioptre after a combined operation. However, there was no significant d ifference between the expected and observed refractive errors. Conclusions: Desp ite an alteration of the axial length and corneal curvature, the refractive outc ome after a combined operation did not differ significantly from the predicted r efraction.
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