苍白球深部脑刺激治疗严重的迟发性肌张力障碍

摘要

In five patients with medically refractory tardive dystonia, continuous bilateral high- frequency stimulation of the globus pallidus internus was associated with a rapid (within 12 to 72 hours) and substantial (mean 87% , 10.7 SD of the motor part of the Burke- Fahn- Marsden Dystonia Rating Scale) improvement of dystonia and functional disability without adverse events.