Background. Data regarding salvage surgery for ovarian immature teratoma (IT) are lacking despite its established role in the management of chemorefractory testicular germ cell tumors. In this report, a case of advanced IT that was salvaged by secondary cytoreduction following failure of both primary therapy and salvage chemotherapy is described, and the available literature is reviewed. Case. A 28- year- old patient underwent primary cytoreductive surgery followed by platinum- based chemotherapy for stage IIIC, grade 3, ovarian IT. Second- line chemotherapy was administered after residual disease was identified at second- look surgery. Following failure of salvage chemotherapy, aggressive secondary debulking resulted in long- term diseasefree survival of over 48 months. Conclusion. There appears to be a distinct role for salvage surgery in selected cases of chemorefractory IT. More studies are needed to further define the subset of patients who benefit most from this management approach.
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