中国非吸烟女性环境烟草烟雾暴露与肺癌风险的 Meta 分析

摘要

Objective to explore the relationship between environment tobacco smoke exposure among non-smoking women in China and lung cancer risk. Methods we collected case-control studys on ETS exposure among Chinese non-smoking women and lung cancer risk. The quality of included case-control studies were evaluated and Meta analysis was conducted. Results 12 articles were included, total cases3963 and controls 4878.Combined results showed that ETS exposure among Chinese non-smoking women were found to be significantly associated with lung cancer ris, which combined OR(95%CI)were1.33(1.20-1.47). Conclusion ETS was a significant risk of lung cancer among Chinese non-smoking women.%目的：分析中国非吸烟女性环境烟草烟雾暴露（environmental tobacco smoke，ETS）与肺癌发生危险之间的关系。方法纳入有关中国非吸烟女性 ETS 暴露与肺癌发生关联的病例-对照研究，对纳入研究的质量进行评价，并进行 Meta 分析。结果最终纳入12篇文献，累计肺癌病例3963例，对照4878例，合并分析结果显示 ETS 暴露与非吸烟女性肺癌发生的关联有统计学意义，合并 OR（95%CI）值为1.33（1.20-1.47）。结论 ETS 是中国非吸烟女性肺癌发生的重要危险因素。