Research Progress on the Intervening Effects of Active Components of Chinese Herbs on Amyloid-Beta-Induced Injury of Neural Cells

摘要

Alzheimer's disease is a common clinical central nervous system degenerative disease. From 1906, it has not yet been clearly revealed the pathogenesis, and there are no clinically safe and effective drugs. Amyloid?beta (Aβ) cascade reaction theory is currently recognized as the pathogenesis.Aβ deposition of neurotoxicity is an important part of the pathogenesis. There areAβ?induced inflammation of the central nervous and oxidative stress?induced apoptosis induced by a variety of ways leading to neuronal dysfunction and death. This article summarizes the active ingredients of traditional Chinese medicine that has a protective effect on Aβ toxicity in recent years. Traditional Chinese medicine mainly through the antiapoptosis, antioxidation, and anti?inflammatory reduces Aβ production and deposition of Aβ on the protection of nerve cell injury.