Hepatitis B virus(HBV) infection is a global public health problem that concerns 350 million people worldwide.Individuals with chronic hepatitis B(CHB) are at increased risk of developing liver cirrhosis,hepaticde-compensation a nd hepatocellular carcinoma.To maintain undetectable viral load reduces chronic infection complications.There is no treatment that eradicates HBV infection.Current drugs are expensive,are associated with adverse events,and are of limited efficacy.Current guidelines try to standardize the clinical practice.Nevertheless,controversy remains about management of asymptomatic patients with CHB who are hepatitis B e antigen(HBeAg)-positive with normal alanine aminotransferase,and what is the cut-off value of viral load to distinguish HBeAg-negative CHB patients and inactive carriers.We discuss in detail why DNA level alone is not sufficient to begin treatment of CHB.
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机译:marcadores serologicos de Hepatitis Viral B en pacientes Drogadictos del Hospital Hermilio Valdizan,peru,peru(秘鲁利马Hermilio Valdizan医院药物成瘾患者的病毒性乙型肝炎血清学标志物)。 (重新公布新的可用性信息)。