Second Mil Med Univ;
Changhai Hosp;
Dept Infect Dis;
Shanghai 200433;
Peoples R China;
Second Mil Med Univ;
Dept Biochem & Mol Biol;
Shanghai 200433;
Peoples R China;
Programmed death type-1; Hepatitis B virus; Chronic hepatitis B; Natural stage; CD8+T cell; Serum viral load; Programmed death ligand; T cell response;