The purpose of this study was to evaluate the perioperative complications in fetoscopy-guided laser therapy in feto-fetal transfusion syndrome. Study design: Details of feto-fetal transfusion syndrome cases who were delivered between 1999 and 2004 in a single center were reviewed retrospectively. Results: One hundred seventy-five procedures were performed percutaneously with the use of local anesthesia. Survival at 6 months of at least 1, 1, and 2 babies was 73% , 38% , and 35% , respectively. Placental abruption and miscarriage was diagnosed in 3 and 12 cases, respectively. Premature rupture of membranes occurred in 49 cases (28% ) and including 12, 29, and 46 cases that occurred before 24, 28, and 34 weeks of gestation, respectively. The entry of the trocar was transpla- cental in 48 cases (27% ), but it was not associated with miscarriage (P = .26), premature rupture of membranes (P = .58), or placental abruption (P = .37). Conclusion: Fetoscopic laser treatment of feto-fetal transfusion syndrome can be performed percutaneously with local anesthesia without significant maternal morbidity. Transplacental entry was not associated with premature rupture of membranes or miscarriage.
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