目的:研究代谢综合征患者痰湿内蕴辨证与血清脂联素、血脂、SOD之间的关系,为中医辨证代谢综合征寻找客观依据以便更好地指导临床治疗.方法:共收集代谢综合征患者49例,辨证分为痰湿内蕴型25例,非痰湿内蕴型24例;另设20例我院门诊健康体检者为对照组.测量患者的血清脂联素、血脂、SOD,分析脂联素、血脂、SOD与痰湿内蕴辨证之间的关系.结果:2组代谢综合征患者的血清脂联素和超氧化物歧化酶低于对照组,差异有统计学意义.代谢综合征患者2组比较,痰湿内蕴组脂联素水平低于非痰湿内蕴组,2组SOD水平无明显差异.结论:代谢综合征患者存在低脂联素血症,代谢综合征患者痰湿内蕴辨证与脂联素有直接相应关系,脂联素水平可作为辨证代谢综合征的客观指标及疗效参考依据.%Objective:To investigate how metabolic syndrome due to phlegm-dampness accumulation is related to adiponectin, superoxide dismutase( SOD), and blood lipid, aiming to find out objective evidences in support of differentiation of metabolic syndrome and better guide clinical treatment. Methods: Forty-nine patients with metabolic syndrome were differentiated as phlegm-dampness accumulation ( n = 25 ) and non-accumulation ( n = 24), compared with 20 healthy persons. Levels of adiponectin, SOD, blood fat were detected respectively. Results: Levels of adiponectin and SOD were significantly lower in metabolic syndrome patients than in the healthy population. Adiponectin level was lower in the accumulation group than in the non- accumulation group. Conclusion: Metabolic syndrome patients presented low level of adiponectin. Adiponectin is closely related to the syndrome of phlegm-dampness accumulation, thus could be an objective evidence for syndrome differentiation and efficacy evaluation.
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