腕踝针联合血府逐淤汤治疗急性腰扭伤的临床效果及其对血液学炎性反应指标的影响

摘要

Objective:To investigate the clinical effects of wrist-ankle acupuncture combined with Xuefu Zhuyu Decoction in treating acute lumbar sprain and the effects on the level of IL-6,IL-10,PGE2,ESR and hs-CRP of the hematological inflammatory indexes.Methods:We divided 124 patients with acute lumbar sprain,hospitalized from December 2014 to December 2016,into observation group and control group in accordance with the random number table,62 patients in each group.Patients in the control group were given wrist-ankle acupuncture therapy while patients in the observation group additionally took Xuefu Zhuyu Decoction on the basis of treatment for the control group.The clinical therapeutic effect,VAS score,the M-JOA score,ODI score,the hematological inflammatory indexes of IL-6,IL-10,PGE2,ESR and hs-CRP level were observed from the two group.Results:There was no statistical difference comparatively between the two groups in ODI score,the level of IL-6,IL-10,PGE2,ESR and hs-CRP (P ＞0.05).After treatment,the VAS,M-JOA,ODI score,the level of IL-6,IL-10,PGE2,ESR and hs-CRP of the observation group were lower than the control group.There were statistical differences comparatively between the two groups in VAS,M-JOA,ODI score,the level of IL-6,IL-10,PGE2,ESR and hs-CRP (P ＜0.05).The total effective rate of the observation group (90.32％) was obviously higher than that of the control group (75.81％) in treatment,there were statistical differences between the two groups (P ＜0.05) comparatively.The rate of adverse reactions of the control group was 3.23％ and the observational group was 6.45％,so there was no statistical difference between the two groups (P ＞ 0.05).Conclusion:Xuefu Zhuyu Decoction can treat acute lumbar sprain by improving microcirculation,dilate peripheral blood vessels,strengthen tissue aerobic metabolism,boost the metabolism of inflammatory mediators and lower blood inflammatory indexes.It is worthy of clinical application for that it can relieve flank pain as well as it has less adverse reactions.%目的:探究腕踝针联合血府逐瘀汤治疗急性腰扭伤的临床效果及其对血液学炎性反应指标IL-6、IL-10、PGE2、ESR、hs-CRP水平的影响.方法:选取2014年12月至2016年12月鄂东医疗集团黄石市中心医院收治的急性腰扭伤患者124例,按随机数字表法随机分为观察组和对照组,每组62例.对照组给予腕踝针灸疗法,观察组在对照组治疗的基础上加用血府逐瘀汤.观察2组患者临床治疗效果、VAS评分、M-JOA评分、ODI评分、血液学炎性反应指标IL-6、IL-10、PGE2、ESR、hs-CRP水平以及不良反应发生情况.结果:2组患者治疗前VAS、M-JOA、ODI评分、IL-6、IL-10、PGE2、ESR、hs-CRP水平比较不具有统计学意义(P＞0.05);与对照组治疗后比较,观察组治疗后VAS、M-JOA、ODI评分、IL-6、IL-10、PGE2、ESR、hs-CRP水平明显降低,2组患者治疗后VAS、M-JOA、ODI评分、IL-6、IL-10、PGE2、ESR、hs-CRP水平比较,差异有统计学意义(P＜0.05).观察组的治疗总有效率(90.32％)明显高于对照组(75.81％),2组比较,差异有统计学意义(P＜0.05).对照组不良反应发生率为3.23％,观察组为6.45％,2组在不良反应发生率上不具有统计学意义(P＞0.05).结论:血府逐瘀汤在治疗急性腰扭伤中可通过改善微循环,扩张周围血管,加强组织有氧代谢,加速炎性递质代谢,降低血液炎性反应指标,从而缓解腰部疼痛,且不良反应少,值的临床推广使用.