History of recurrent miscarriage in traditional Chinese medicine literature

摘要

Recurrent miscarriage (RM) as a gynecological disorder was recognized by traditional Chinese medicine (TCM) practitioners long before the age of modern medicine. TCM physicians reported and recorded RM in the canonical TCM literature, which dates back more than 1500 years. The first cases of RM as a fertility abnormality were reported in Chanjing, which was written during the Nanbei Dynasty of China (420 A.D. – 589 A.D.). Some prescriptions for the treatment of RM are still actively used by modern TCM practitioners. In addition, many recent pharmacological and clinical studies have focused on the TCM therapy for RM. To identify the new therapeutic targets for RM and further promote the interest in treating RM with TCM, we reviewed the etiology, pathogenesis, treatment, and prevention of RM discussed both in the TCM literature and in contemporary pharmacological and clinical studies.%早在1500多年前,中医古籍对复发性流产就有相应的记载.最早把复发性流产当成生殖异常的记载出现在南北朝时期的古籍《产经》上(420 A.D.–589 A.D.),许多治疗复发性流产的经典方剂沿用至今.本文回顾了历代医家对复发性流产的病因病机及治疗的认识,列出了中医治疗复发性流产的经典方,以及现代医学中关于复发性流产的药理学研究和临床研究.