医用近β型TLM合金的超亲水表面改性

摘要

医用近β型钛合金TLM(Ti - 25Nb - 3Zr - 2Sn - 3Mo)具有优良的力学和生物学性能.TLM合金经过NaOH溶液处理后表面形成了钛(铌)酸钠凝胶层,再经过稀HCl浸泡后转化为氧化钛(铌)凝胶层.经过2.5 mol/L NaOH(12 h)-HCl处理的TLM合金表面形成了纳米多孔凝胶层,15 min紫外照射处理后达到超亲水(接触角＜5°).血液相容性实验表明,超亲水TLM合金试样表面黏附的血小板数量少于磨光TLM试样.因此,超亲水表面改善了TLM合金的血液相容性.%Medical nearβ-type titanium alloy of TLM (Ti-25Nb-3Zr-2Sn-3Mo) has good mechanical and biological properties. When TLM alloy is subjected to the NaOH solution treatment, sodium titanate (niobate) gel layer will be formed on the surface, and the gel layer will be converted into titania ( niobium oxide) gel layer after the dilute HC1 treatment. The TLM sample with 2.5 mol/L NaOH(12 h)-HCl treatment has nano porous gel layer, and becomes superhydrophilic (contact angle <5°) after UV irradiation treatment for 15 min. The blood compatibility tests show that the superhydrophilic TLM sample has less platelet adhesion on the surface than the ground TLM sample. Thus, the superhydrophilic surface has improved blood compatibility of the TLM alloy.