Objective To evaluate the long-term prognostic capacity of the SYNTAX score Ⅱ(SxScore Ⅱ) and SYNTAX score (SxScore) in patients undergoing left main percutaneous coronary intervention (LM-PCI). Methods A total of 209 patients undergoing unprotected LM-PCI in the Cardiology Department of the Affiliated Hospital of PAP of Logistic College were prospectively collected. Follow up was carried out by telephone or outpatient or rehospitalization. The clinical endpoint focused on MACCE after PCI including composite death, nonfatal myocardial infarction, target vessel revascularization and stroke. The secondary endpoint included cardiac death and stent thrombosis. The SxScore and SxScoreⅡ were retrospectively calculated according to results of coronary angiography and clinical features of patients. Patients were stratified according to tertiles of low (≤22), intermediate (23-32), and high (≥33). The clinical data were comparedbetween three groups. The predictive ability of two scoring systems to MACCE after PCI was compared by COX regression evaluation. Results In 209 patients, 12 patients were lost to follow-up (5.7%), and the median follow-up was 30.2 months, 56 cases (28.4%) were observed to suffer from MACCE. The incidence rates of MACCE were 19.0%, 28.6%and 44.4%in SxScore low, intermediate and high groups respectively. The incidence rates of MACCE were 12.8%, 23.8%and 45.5%in SxScoreⅡlow, intermediate and high groups respectively. Single factor analysis showed that SxScore, SxScoreⅡ, age, diabetes and left ventricular ejection fraction (LVEF) were the independent predictors of MACCE. Multivariate analysis showed that SxScore and SxScoreⅡwere still risk independent predictors for MACCE. Conclusion Both SxScore and SxScoreⅡare independent risk predictors for MACCE in patients with unprotected left main coronary artery disease undergoing PCI treatment.%目的：研究SYNTAX评分（SxScore）和SYNTAXⅡ评分（SxScoreⅡ）对无保护左主干（ULMCA）冠心病患者接受经皮冠状动脉介入治疗（PCI）术后30个月的主要不良心脑血管事件（MACCE）的预测能力。方法回顾性分析武警后勤学院附属医院心内科接受PCI治疗的209例ULMCA冠心病患者，通过电话、门诊和（或）再次入院随访患者PCI术后的MACCE，包括全因死亡、非致命性心肌梗死、靶血管血运重建、卒中及次要终点事件包括心源性死亡、支架内血栓。根据冠状动脉造影结果及临床特征计算SxScore和SxScoreⅡ，根据SxScore标准分为低分组≤22分，中分组23～32分，高分组≥33分，比较3组的临床资料，Cox回归评价两种评分系统对PCI术后MACCE的预测能力。结果209例患者中，失访12例（5.7%），中位随访时间为30.2个月，56例（28.4%）观察到MACCE。SxScore低、中、高分组的MACCE发生率分别为19.0%，28.6%和44.4%。SxScoreⅡ低、中、高分组的MACCE发生率分别为12.8%、23.8%和45.5%。单因素分析结果显示SxScore、SxScoreⅡ高分值、高龄、合并糖尿病和低左室射血分数（LVEF）为MACCE的危险因子，多因素分析结果显示SxScore、SxScoreⅡ高分值仍为MACCE的独立危险因子。结论 SxScore和SxScoreⅡ对冠状动脉ULMCA病变患者行PCI治疗后的MACCE均有预测作用。
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