针对我国精准医学发展的现状，从加强科技情报意识、加强对美国科研发展的信息跟踪与了解、注重情报研究、建立中国精准医学科研情报平台和协调中心、重视事实型数据库、组织人才数据库、项目数据库以及专利专题数据库、建立科研情报机制、加大科技情报人才队伍的建设力度6个方面探讨了科研情报在精准医学行业中的重要性，旨在为相关企业和决策部门在精准医学发展中如何发挥科技情报的独特作用和价值提供可借鉴的思考。%This paper identifies a number of high-value scientific opportunities or use cases that could be used to inform the design of the Precision Health & Medicine Initiative in China. These use cases include development of quantitative estimates of risk for a range of diseases by integrating environmental exposures, genetic factors, and gene-environment interactions; identification of determinants of individual variation in efifcacy and safety of commonly used therapeutics; discovery of biomarkers that identify people with increased or decreased risk of developing common diseases; use of mobile health (mHealth) technologies to correlate activity, physiologic measures and environmental exposures with health outcomes; determination of the health impact of heterozygous loss of function mutations; development new disease classiifcations and relationships; empowerment of participants with data and information to improve their own health; and creation of a platform for formal investigations of whether and how data are used by participants and ways to promote information use by individuals. As a result, it is expected that the Intelligence Platform will be a transformative platform for the understanding of health and disease.
展开▼
