某三级甲等综合医院2014-2015年364例中成药不良反应分析

摘要

目的 了解三级甲等综合医院中成药不良反应的特点.方法 回顾性分析2014-2015年某三级甲等综合医院364例中成药不良反应的相关资料.结果 364例中成药不良反应中男女比为1.15∶1,多发生于50岁以上者(59.6％),多为一般不良反应(75.0％),转归较好,多由注射剂导致(82.1％).引发不良反应例次最高的药物种类为理血剂(57.7％),其次为补益剂和清热剂.中成药不良反应最常累及器官为皮肤及其附件(36.0％),其次为胃肠系统和神经系统.结论 三级甲等综合医院中成药不良反应具有一定特点,应加强不良反应监测和综合治理,提高中成药用药安全.%Objective To investigate the characteristics of adverse reactions of Chinese patent medicine in a triple A general hospital.Methods The relevant data of 364 cases of adverse reaction caused by Chinese patent medicine in a triple A general hospital from 2014 to 2015 were analyzed retrospectively.Results The ratio of male to female was 1.15 ∶ 1 in 364 cases of adverse reaction of Chinese patent medicine.Most of the adverse reactions (59.6％) occurred in the age of 50 years or older.The vast majority (75.0％) of adverse reactions are not serious adverse reactions.82.1％ of the adverse reactions were caused by injections,and had a relatively good prognosis.The vast majority of adverse reactions were caused by blood-regulating formula (57.7％),tonic formulae and heatclearing prescription.The adverse reactions of Chinese patent medicine often involved the skin and its appendages (36.0％),followed by gastrointestinal system and nervous system.Conclusion The adverse reaction caused by Chinese patent medicine in a triple A general hospital has certain characteristics.The monitoring and comprehensive treatment of the adverse reactions caused by Chinese patent medicine should be strengthened,in order to improve the safety of the use of Chinese patent medicine.