目的：探究不同抗菌药物与舒巴坦联合治疗多重耐药鲍曼不动杆菌（Ab）肺炎的临床疗效。方法：将80例多重耐药 Ab 肺炎患者分为 A 组（30例）、B 组（30例）和 C 组（20例），分别采用替加环素、多粘菌素 E 和比阿培南联合舒巴坦治疗，比较3组临床治疗效果。结果：A 组和 B 组治疗总有效率（93．3％、90．0％）和细菌清除率（66．7％、66．3％）均高于 C 组（76．7％、40．0％）（P ＜0．05）；A 组和 C 组用药不良反应发生率（6．7％、5．0％）均低于 B 组（20．0％）（P ＜0．05）。结论：与多粘菌素 E 、比阿培南相比，替加环素联合舒巴坦治疗多重耐药 Ab 肺炎效果更为理想。%Objective :To explore the clinical effect of different antimicrobial agents combined with com‐bined with sulbactam in the treatment of multiple drug‐resistant AB pneumonia .Methods :80 cases with multiple drug‐resistant AB pneumonia were divided into the A group (30 cases) and B group (30 cases) and C group (20 ca‐ses) randomly .They were given the Tigecycline polymyxin E and biapenem combined with sulbactam randomly . The clinical curative effects of the three groups were compared .Results :Total effective rate and bacterial clearance rate of group A and group B (93 .3% ,90 .0% ) (66 .7% ,66 .3% ) were higher than group C (76 .7% ,40 .0% ) ,the difference was significant statistically significant (P< 0 .05) .The drug adverse reaction rate of group A and group C (6 .7% ,5 .0% ) were lower than that of group B (20 .0% ) ,the difference was significant statistically significant (P< 0 .05) .Conclusion :Compared with polymyxin E and biapenem , Tigecycline combined with sulbactam on the treatment of multiple drug‐resistant AB pneumonia has more ideal effect .
展开▼
